目的：探讨无痛胃肠镜麻醉患者中采取丙泊酚和纳布啡麻醉时的效果。方法：2022 年1 月~2023 年1 月，挑选57 例我院接受无痛胃肠镜检查的患者，随机分为研究组、对照组。研究组实行纳布啡复合丙泊酚麻醉，对照组采用丙泊酚复合舒芬太尼麻醉，比较两组麻醉效果。结果：研究麻醉满意率高于对照组，不良反应低于对照组，另外比较两组患者麻醉效果以及体征指标，差异具备统计学差异（P<0.05）。结论：无痛胃肠镜麻醉中应用丙泊酚复合纳布啡时，麻醉效果稳定，患者体征指标平稳，不易出现副作用，患者整体的满意度相对较高，相较于丙泊酚复合舒芬太尼而言，应用优势更为明显。

Abstract: Objective To investigate the effect of propofol and nalbuphine in patients with painless gastroenteroscopy. Methods From January 2022 to January 2023, 57 patients receiving painless gastroenteroscopy in our hospital were randomly divided into study group and control group. The study group was anesthetised with nalbuphine combined with propofol, while the control group was anesthetised with propofol combined with sufentanil. Results The satisfaction rate of anesthesia in the study was higher than that in the control group, and the adverse reactions were lower than that in the control group. In addition, the anesthetic effect and physical indicators of the two groups were compared, and the differences were statistically significant (P<0.05). Conclusion When propofol combined with nalbuphine is used in painless gastroenteroscopy anesthesia, the anesthetic effect is stable, the patient’s physical indicators are stable, and the side effects are not easy to occur. The overall satisfaction of patients is relatively high. Compared with propofol combined with sufentanil, the application advantage is more obvious.